Electrolyte deficiency after the novel coronavirus infection and post-COVID asthenia

Asthenia is a non-specific syndrome common in general practice and occurs patients with acute chronic somatic disorders, including infectious ones. The novel coronavirus infection (COVID-19) one of the leading causes severe persistent asthenia. hypothalamicpituitary- adrenal axis essential for development asthenia since its dysfunction provoked by various factors (including infections) results electrolyte metabolism impairment hypokalemia hypomagnesemia. This paper describes hypothetical pathogenic mechanism after COVID-19, which implies over-activation renin-angiotensin-aldosterone system that, particular, leads to hypokalemia. role pharmacotherapy prescribed COVID-19 highlighted. Study demonstrate high rate suggest direct correlation between severity activity viral infection. Furthermore, detection abnormalities both convalescence. Finally, authors consider ways relieving this pathological condition. KEYWORDS: infection, post-infectious asthenia, angiotensin-converting enzyme, hypokalemia, FOR CITATION: Ebzeeva E.Yu., Ostroumova O.D., Krotkova I.F. et al. Electrolyte deficiency post- COVID Russian Medical Inquiry. 2021;5(5):245–251 (in Russ.). DOI: 10.32364/2587-6821-2021-5-5-245-251.